Guts'n Puck Hockey Tournament

The Crohn's and Colitis Foundation of Canada (CCFC)

CCFC LogoThe New Guts'n Pucks (formerly the Electronics Industry) Hockey Tournament has supported The Crohn's and Colitis Foundation of Canada (CCFC) since we began the tournament in 1988. The mission of the CCFC is simple “find a cure”. The Crohn's and Colitis Foundation of Canada (CCFC) is making progress towards finding a cure for IBD, with over $65-million invested in research since the foundation's inception in 1974. To date the EIHT has raised over $400,000 help with research. This disease affects over 200,000 Canadians of all ages and cultural backgrounds.

2007 Award

CCFC Award

This is the Dedicated Grant and Research that We Fund:

THE ARCHAEAL MICROBIOTA IN INFLAMMATORY BOWEL DISEASE (IBD)

W. Ford Doolittle
Dalhousie University

Microbial causes are proven or suspected for most if not all chronic inflammatory disease, including arthritis, chronic gastritis, as well as lower GI inflammatory disease, including ulcerative colitis and Crohn's disease. Host genetic factors such as the NOD2 gene (CARD15) and variations in type and level of antimicrobial peptides (that defend against invading bacteria), as well as an absence of protective flora, all likely contribute to these complex diseases. Plaque for our Research Grant No single microbe, however, has unequivocally been proven to cause IBD, though the majority of gut microbes have never been cultured. This study will be the first to test a conjecture that archaea (micro-organisms that have yet to be defined through independent culture analysis) play a role (as causative or protective agents) in Crohn's disease and ulcerative colitis, in the first truly comprehensive assessment of archaeal diversity in inflammatory bowel disease patients. Researchers hope to determine which archaea are present in the bowel flora and associated tissues of healthy individuals, and whether there is a difference in diversity and prevalence of archaea between patients with inflammatory bowel disease and healthy individuals; whether there are such difference between patients with these two conditions, and whether there are such differences between different tissues and locations within patients. On the basis of the information obtained, researchers hope to devise novel therapeutics for existing cases and proactive therapeutic strategies to prevent the onset of IBD in identifiable high risk groups.

To Learn More about the CCFC:

Visit the CCFC web site to get more information on the research, the various grants, how to contribute directly and how to volunteer for the CCFC.

 

 

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